Article
Diabetic Phenotype in the Small Intestine of Zucker Diabetic Fatty Rats.
Digestion - 1 Jan 2016
Hvid Henning, Jensen Stina Rikke, Witgen Brent M, Fledelius Christian, Damgaard Jesper, Pyke Charles, Rasmussen Thomas Bovbjerg
Abstract excerpt
BACKGROUND/AIMS: In contrast to streptozotocin (STZ)-induced rodent models of diabetes, there are no thorough characterizations of the intestinal phenotype and the underlying changes in the global gene-expression of genetic models of diabetes, such as the Zucker diabetic fatty (ZDF) rat. The aim of the present study was to characterize the intestine in the ZDF rat. METHODS: The intestine of ZDF rats and lean...
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