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A population study using the human erythrocyte PIG-A assay.

Environmental and molecular mutagenesis - 1 Oct 2016

Cao Yiyi, Yang Li, Feng Nannan, Shi Oumin, Xi Jing, You Xinyue, Yin Chunrong, Yang Huan, Horibata Katsuyoshi, Honma Masamitsu, Qian Biyun, Weng Wei, Luan Yang

Abstract excerpt

Erythrocyte-based PIG-A assay is sensitive and reliable in detecting exposure to mutagenetic agents in animal studies, but there are few data from human populations. In this study, we employed a method for detecting CD59 phenotypic variants, resulting from mutation in the PIG-A gene, in human red blood cells (RBCs), and determined the CD59-deficient RBC (RBCCD59- ) frequencies in 217 subjects from general...

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PMID: 27581231
DOI: 10.1002/em.22040

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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