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The PIG-A gene mutation assay in human biomonitoring and disease

2023-08-25

Abstract excerpt

The blood cell phosphatidylinositol glycan class A ( PIG-A ) gene mutation assay has been extensively researched in rodents for in vivo mutagenicity testing and is now being investigated in humans. The PIG-A gene is involved in glycosyl phosphatidylinositol (GPI)-anchor biosynthesis. A single mutation in this X-linked gene leads to loss of membrane bound GPI-anchors, which can be enumerated using flow cytometry...

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Literature Corpus work
f98b7dc6-aba2-5ed5-9fca-c8639010a209
DOI
10.22541/au.169297383.32985514/v1
Open publication

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The PIG-A gene mutation assay in human biomonitoring and diseaseDOI 10.22541/au.169297383.32985514/v1
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