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Article

Leukemogenic Activity of Cohesin Rings True.

Cell stem cell - 3 Dec 2015

Williams Mark S, Somervaille Tim C P

Abstract excerpt

Cohesin complex components are frequently mutated in human myeloid cancers. Three new studies now show that cohesin mutations disrupt the differentiation of normal hematopoietic stem and progenitor cells and enhance self-renewal, shedding light on how these alterations may contribute to leukemic transformation.

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Source

Identifiers

PMID: 26637939
DOI: 10.1016/j.stem.2015.11.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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