Article
A strong association of human leukocyte antigen-associated Pol and Gag mutations with clinical parameters in HIV-1 subtype A/E infection.
AIDS (London, England) - 13 Mar 2016
Van Tran Giang, Chikata Takayuki, Carlson Jonathan M, Murakoshi Hayato, Nguyen Dung Hoai, Tamura Yoshiko, Akahoshi Tomohiro, Kuse Nozomi, Sakai Keiko, Sakai Sachiko, Cobarrubias Kyle, Oka Shinichi, Brumme Zabrina L, Van Nguyen Kinh, Takiguchi Masafumi
Abstract excerpt
OBJECTIVES: Identification of human leukocyte antigen-associated HIV-1 polymorphisms (HLA-APs) in different global populations furthers our understanding of HIV-1 pathogenesis and may help identify candidate immunogens for HIV vaccines targeted to these populations. Although numerous population-based studies identifying HLA-APs have been conducted in HIV-1 subtype B- and subtype C-infected cohorts, few have...
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