HLA-A*7401-mediated control of HIV viremia is independent of its linkage disequilibrium with HLA-B*5703.

doi:10.4049/jimmunol.1003711

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Article

HLA-A7401-mediated control of HIV viremia is independent of its linkage disequilibrium with HLA-B5703.

Journal of immunology (Baltimore, Md. : 1950) - 15 May 2011

Matthews Philippa C, Adland Emily, Listgarten Jennifer, Leslie Alasdair, Mkhwanazi Nompumelelo, Carlson Jonathan M, Harndahl Mikkel, Stryhn Anette, Payne Rebecca P, Ogwu Anthony, Huang Kuan-Hsiang Gary, Frater John, Paioni Paolo, Kloverpris Henrik, Jooste Pieter, Goedhals Dominique, van Vuuren Cloete, Steyn Dewald, Riddell Lynn, Chen Fabian, Luzzi Graz, Balachandran Thambiah, Ndung'u Thumbi, Buus Søren, Carrington Mary, Shapiro Roger, Heckerman David, Goulder Philip J R

Abstract excerpt

The potential contribution of HLA-A alleles to viremic control in chronic HIV type 1 (HIV-1) infection has been relatively understudied compared with HLA-B. In these studies, we show that HLA-A*7401 is associated with favorable viremic control in extended southern African cohorts of >2100 C-clade-infected subjects. We present evidence that HLA-A*7401 operates an effect that is independent of HLA-B*5703, with...

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PMID: 21498667
DOI: 10.4049/jimmunol.1003711
PMCID: PMC3738002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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