Article
Molecular characterization of HIV-1 CRF01_AE in Mekong Delta, Vietnam, and impact of T-cell epitope mutations on HLA recognition (ANRS 12159).
PloS one - 1 Jan 2011
Lazaro Estibaliz, Tram Luong Thu, Bellecave Pantxika, Guidicelli Gwenda-Line, Anies Guerric, Thu Huynh Hoang Khanh, Debelleix Marie Pillot, Vray Muriel, Recordon-Pinson Patricia, Taupin Jean-Luc, Lien Truong Thi Xuan, Fleury Herve
Abstract excerpt
BACKGROUND: To date, 11 HIV-1 subtypes and 48 circulating recombinant forms have been described worldwide. The underlying reason why their distribution is so heterogeneous is not clear. Host genetic factors could partly explain this distribution. The aim of this study was to describe HIV-1 strains circulating in an unexplored area of Mekong Delta, Vietnam, and to assess the impact of optimal epitope mutations on...
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