Article
HLA Class I-Mediated HIV-1 Control in Vietnamese Infected with HIV-1 Subtype A/E.
Journal of virology - 1 Mar 2018
Chikata Takayuki, Tran Giang Van, Murakoshi Hayato, Akahoshi Tomohiro, Qi Ying, Naranbhai Vivek, Kuse Nozomi, Tamura Yoshiko, Koyanagi Madoka, Sakai Sachiko, Nguyen Dung Hoai, Nguyen Dung Thi, Nguyen Ha Thu, Nguyen Trung Vu, Oka Shinichi, Martin Maureen P, Carrington Mary, Sakai Keiko, Nguyen Kinh Van, Takiguchi Masafumi
Abstract excerpt
HIV-1-specific cytotoxic T cells (CTLs) play an important role in the control of HIV-1 subtype B or C infection. However, the role of CTLs in HIV-1 subtype A/E infection still remains unclear. Here we investigated the association of HLA class I alleles with clinical outcomes in treatment-naive Vietnamese infected with subtype A/E virus. We found that HLA-C*12:02 was significantly associated with lower plasma...
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