Article
Xist imprinting is promoted by the hemizygous (unpaired) state in the male germ line.
Proceedings of the National Academy of Sciences of the United States of America - 24 Nov 2015
Sun Sha, Payer Bernhard, Namekawa Satoshi, An Jee Young, Press William, Catalan-Dibene Jovani, Sunwoo Hongjae, Lee Jeannie T
Abstract excerpt
The long noncoding X-inactivation-specific transcript (Xist gene) is responsible for mammalian X-chromosome dosage compensation between the sexes, the process by which one of the two X chromosomes is inactivated in the female soma. Xist is essential for both the random and imprinted forms of X-chromosome inactivation. In the imprinted form, Xist is paternally marked to be expressed in female embryos. To...
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