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Article

Effect of TSIX disruption on XIST expression in male ES cells.

Cytogenetic and genome research - 1 Jan 2002

Sado T, Li E, Sasaki H

Abstract excerpt

XIST and its antisense partner, TSIX, encode non-coding RNAs and play key roles in X chromosome inactivation. Targeted disruption of TSIX causes ectopic expression of XIST in the extraembryonic tissues upon maternal transmission, which subsequently results in embryonic lethality due to inactivation of both X chromosomes in females and a single X chromosome in males. TSIX, therefore, plays a crucial role in...

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Share to Embryo, Mammalian
Share to Gene Expression Regulation
Share to In Situ Hybridization, Fluorescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Reverse Transcriptase Polymerase Chain Reaction

Share to RNA, Long Noncoding

Share to RNA, Untranslated

Share to Stem Cells

Source

Identifiers

PMID: 12900553
DOI: 10.1159/000071582

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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