Article
NK sensitivity, H-2 expression and metastatic potential: analysis of H-2Dk gene transfected fibrosarcoma cells.
Journal of immunogenetics - 1 Jan 2000
Gopas J, Rager-Zisman B, Har-Vardi I, Hammerling G J, Bar-Eli M, Segal S
Abstract excerpt
We have used the 3-Methylcholanthrene induced T-10 fibrosarcoma tumour cell system (H-2b xH-2k)F1 to elucidate the possible correlation between metastatic potential, expression of individual H-2 antigens and susceptibility to NK cells. Transfection of the non-metastatic and NK sensitive IC9 cells...
Topics
- Animals
- Antibodies, Monoclonal
- Complement System Proteins
- Cytotoxicity, Immunologic
- Fibrosarcoma
- H-2 Antigens
- Histocompatibility Antigen H-2D
- Killer Cells, Natural
- Methylcholanthrene
- Mice
- Mice, Inbred BALB C
- Phenotype
- Transfection