MHC class I genes controlling the metastatic phenotype of tumor cells.

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Article

MHC class I genes controlling the metastatic phenotype of tumor cells.

Seminars in cancer biology - 1 Oct 1991

Feldman M, Eisenbach L

Abstract excerpt

Metastatic clones of murine tumors that manifest impaired expression of class I MHC antigens do not induce an antitumor CTL activity. Transfection of H-2Kb genes into D122 carcinoma and B16 melanoma clones converted these cells to low metastatic immunogenic clones that can be used to protect in v...

Topics

Animals
Antigens, Neoplasm
Base Sequence
Gene Expression Regulation, Neoplastic
Genes, MHC Class I
H-2 Antigens
Major Histocompatibility Complex
Mice
Molecular Sequence Data
Neoplasm Metastasis
Neoplasm Proteins
Neoplasm Transplantation
Neoplasms, Experimental
Oncogenes
Phenotype
Proto-Oncogene Proteins c-fos
Proto-Oncogene Proteins c-jun
Rats

Source

Open in PubMed

Identifiers

PMID: 1773049

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1773049-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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