H-2Kb transfection of B16 melanoma cells results in reduced tumourigenicity and metastatic competence.

doi:10.1111/j.1744-313x.1989.tb00475.x

Back to search

Article

H-2Kb transfection of B16 melanoma cells results in reduced tumourigenicity and metastatic competence.

Journal of immunogenetics - 1 Jan 2000

Porgador A, Feldman M, Eisenbach L

Abstract excerpt

The metastatic B16 mouse melanoma shows a low cell surface expression of H-2Kb and H-2Db class I antigens on cells of both the high-metastatic line B16-F10 and the low-metastatic line B16-F1. Similarly, newly generated clones of these lines, having different metastatic properties, all express low...

Topics

Animals
Base Sequence
Clone Cells
Cytotoxicity, Immunologic
H-2 Antigens
Immunocompetence
Melanoma, Experimental
Mice
Mice, Inbred C57BL
Molecular Sequence Data
Phenotype
Transfection

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.