Article
H-2Kb transfection of B16 melanoma cells results in reduced tumourigenicity and metastatic competence.
Journal of immunogenetics - 1 Jan 2000
Porgador A, Feldman M, Eisenbach L
Abstract excerpt
The metastatic B16 mouse melanoma shows a low cell surface expression of H-2Kb and H-2Db class I antigens on cells of both the high-metastatic line B16-F10 and the low-metastatic line B16-F1. Similarly, newly generated clones of these lines, having different metastatic properties, all express low levels of major histocompatibility antigens. One of these clones, the high-metastatic F10.9, was transfected with...
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