Article
Resistance to NK and metastatic potential of fibrosarcoma cells is associated with products encoded by the H-2D region.
Seminars in cancer biology - 1 Oct 1991
Rager-Zisman B, Aboud M, Gopas J, Har-Vardi I, Hämmerling G J, Segal S
Abstract excerpt
We have used the murine 3-methylcholanthrene induced T10 fibrosarcoma tumor cell system originating in (C3II/en x C57BL/6)F1 mice (H-2b x H-2k) to elucidate the possible correlation between metastatic potential, expression of individual H-2 antigens and susceptibility to NK cells. Transfection of...
Topics
- Animals
- Antigens, Neoplasm
- Base Sequence
- Cytotoxicity, Immunologic
- Fibrosarcoma
- H-2 Antigens
- Histocompatibility Antigen H-2D
- Killer Cells, Natural
- Methylcholanthrene
- Mice
- Mice, Inbred AKR
- Mice, Inbred C3H
- Mice, Inbred C57BL
- Molecular Sequence Data
- Neoplasm Metastasis
- Phenotype
- Transfection