Article
H-2Kb and H-2Db gene transfections in B16 melanoma differently affect non-immunological properties relevant to the metastatic process. Involvement of integrin molecules.
International journal of cancer - 15 Oct 1994
De Giovanni C, Nicoletti G, Sensi M, Santoni A, Palmieri G, Landuzzi L, Nanni P, Lollini P L
Abstract excerpt
Modification of non-immunological cell adhesion properties plays a major role in the decrease in metastatic ability observed after transfection of the H-2Kb gene in H-2-negative B16-derived melanoma clone cells. To investigate the role played by different class-I major histocompatibility complex (MHC) genes on non-immunological properties relevant for metastasis, transfection with the H-2Db gene alone or in...
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