Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Selective upregulation of MHC class I expression in metastatic colonies derived from tumor clones of a murine fibrosarcoma.

International journal of clinical & laboratory research - 1 Jan 1999

Pedrinaci S, Algarra I, Garcia Lora A, Gaforio J J, Perez M, Garrido F

Abstract excerpt

Eighteen metastatic nodes derived from the wild-type (GR9) and from 4 different clones (G2, D8, B10, and B9) obtained from a fibrosarcoma were analyzed for H-2 class I and II expression, as well as for adhesion molecules (CD44, CDIIb, CD18, CD49, and CD54). When metastatic nodes were cultured, typed for H-2 antigens, and compared with the H-2 expression of the inducing tumor cell, H-2 Kd and Dd class I expression...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Surface
Share to CD18 Antigens

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fibrosarcoma

Share to Hyaluronan Receptors

Share to Intercellular Adhesion Molecule-1

Share to Killer Cells, Natural

Share to Macrophage-1 Antigen

Share to Soft Tissue Neoplasms

Source

Identifiers

PMID: 10784379
DOI: 10.1007/s005990050085

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Selective upregulation of MHC class I expression in metastatic colonies derived from tumor clones of a murine fibrosarcoma.PMID 10784379Read ↗

A weakly tumorigenic phenotype with high MHC class-I expression is associated with high metastatic potential after surgical removal of the primary murine fibrosarcoma.Semantic proximity Read ↗

Immunoselection by T lymphocytes generates repeated MHC class I-deficient metastatic tumor variants.Semantic proximity Read ↗

Resistance to NK and metastatic potential of fibrosarcoma cells is associated with products encoded by the H-2D region.Semantic proximity Read ↗

NK sensitivity, H-2 expression and metastatic potential: analysis of H-2Dk gene transfected fibrosarcoma cells.Semantic proximity Read ↗

MHC Intratumoral Heterogeneity May Predict Cancer Progression and Response to ImmunotherapySemantic proximity Read ↗

Generation of MHC class I diversity in primary tumors and selection of the malignant phenotype.Semantic proximity Read ↗

Heterogeneity of MHC-class-I antigens in clones of methylcholanthrene-induced tumors. Implications for local growth and metastasis.Semantic proximity Read ↗

MHC class I genes controlling the metastatic phenotype of tumor cells.Semantic proximity Read ↗

MHC class I-deficient metastatic tumor variants immunoselected by T lymphocytes originate from the coordinated downregulation of APM components.Semantic proximity Read ↗

Differential transcriptional control of the H-2K and H-2D loci of the major histocompatibility complex in fibrosarcoma cells.Semantic proximity Read ↗

H-2Kb and H-2Db gene transfections in B16 melanoma differently affect non-immunological properties relevant to the metastatic process. Involvement of integrin molecules.Semantic proximity Read ↗

Cytokeratin 8-MHC class I interactions: A potential novel immune escape phenotype by a lymph node metastatic carcinoma cell lineSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.