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Article

Relationship between a BDNF gene polymorphism and the brain volume in treatment-naive patients with major depressive disorder: A VBM analysis of brain MRI.

Psychiatry research - 30 Aug 2015

Ide Satoru, Kakeda Shingo, Watanabe Keita, Yoshimura Reiji, Abe Osamu, Hayashi Kenji, Ueda Issei, Kishi Taro, Katsuki Asuka, Umene-Nakano Wakako, Iwata Nakao, Nakamura Jun, Korogi Yukunori

Abstract excerpt

The brain-derived neurotrophic factor (BDNF) relates to basic neuronal functions, such as cell survival, axonal outgrowth, and dendritic growth. The Val66Met polymorphism of the BDNF gene may affect genetic susceptibility to major depressive disorder (MDD). We prospectively investigated the relationship between the Val66Met BDNF genotype and voxel-based morphometry (VBM) findings for first episode and drug-naïve...

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Source

Identifiers

PMID: 26078197
DOI: 10.1016/j.pscychresns.2015.05.016

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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