Article
Neuronal correlates of brain-derived neurotrophic factor Val66Met polymorphism and morphometric abnormalities in bipolar disorder.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jul 2009
Matsuo Koji, Walss-Bass Consuelo, Nery Fabiano G, Nicoletti Mark A, Hatch John P, Frey Benicio N, Monkul Emel S, Zunta-Soares Giovana B, Bowden Charles L, Escamilla Michael A, Soares Jair C
Abstract excerpt
The brain-derived neurotrophic factor (BDNF) Val66Met polymorphism has been proposed as a possible candidate for involvement in the pathophysiology of bipolar disorder (BD). To determine whether an association exists between the BDNF Val66Met genotype and morphometric abnormalities of the brain regions involved in memory and learning in BD and healthy subjects. Forty-two BD patients and 42 healthy subjects were...
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