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Article

Relationship between G1287A of the NET Gene Polymorphisms and Brain Volume in Major Depressive Disorder: A Voxel-Based MRI Study.

PloS one - 1 Jan 2016

Ueda Issei, Kakeda Shingo, Watanabe Keita, Yoshimura Reiji, Kishi Taro, Abe Osamu, Ide Satoru, Moriya Junji, Katsuki Asuka, Hori Hikaru, Iwata Nakao, Nakamura Jun, Korogi Yukunori

Abstract excerpt

BACKGROUND: Earlier studies implicated norepinephrine transporter (NET) gene (SLC6A2) polymorphisms in the etiology of major depressive disorder (MDD). Recently, two single nucleotide SLC6A2 polymorphisms, G1287A in exon 9 and T-182C in the promoter region, were found to be associated with MDD in different populations. We investigated the relationship between the brain volume and these two polymorphisms of the...

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Identifiers

PMID: 26960194
DOI: 10.1371/journal.pone.0150712
PMCID: PMC4784887

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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