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Article

No effect of 5HTTLPR or BDNF Val66Met polymorphism on hippocampal morphology in major depression.

Genes, brain, and behavior - 1 Oct 2011

Cole J, Weinberger D R, Mattay V S, Cheng X, Toga A W, Thompson P M, Powell-Smith G, Cohen-Woods S, Simmons A, McGuffin P, Fu C H Y

Abstract excerpt

Neuroimaging research implicates the hippocampus in the aetiology of major depressive disorder (MDD). Imaging genetics studies have investigated the influence of the serotonin transporter-linked polymorphic region (5HTTLPR) and brain-derived neurotrophic factor (BDNF) Val66Met polymorphism on the hippocampus in healthy individuals and patients with depression (MDD). However, conflicting results have led to...

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Identifiers

PMID: 21692988
DOI: 10.1111/j.1601-183X.2011.00714.x
PMCID: PMC3420971

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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