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Article

SORL1 Gene is Associated with the Conversion from Mild Cognitive Impairment to Alzheimer's Disease.

Journal of Alzheimer's disease : JAD - 1 Jan 2015

Piscopo Paola, Tosto Giuseppe, Belli Chiara, Talarico Giuseppina, Galimberti Daniela, Gasparini Marina, Canevelli Marco, Poleggi Anna, Crestini Alessio, Albani Diego, Forloni Gianluigi, Lucca Ugo, Quadri Pierluigi, Tettamanti Mauro, Fenoglio Chiara, Scarpini Elio, Bruno Giuseppe, Vanacore Nicola, Confaloni Annamaria

Abstract excerpt

Several studies have established the sortilin-related receptor gene (SORL1) as a susceptibility locus for Alzheimer's disease (AD). Single nucleotide polymorphisms of SORL1 reported in literature as being associated with AD were investigated in an Italian case-control data set, and their role as a risk factor of conversion to AD was studied in an independent sample of subjects diagnosed with mild cognitive...

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Identifiers

PMID: 25881907
DOI: 10.3233/JAD-141551

Genes

SORL1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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