Article
A study of the SORL1 gene in Alzheimer's disease and cognitive function.
Journal of Alzheimer's disease : JAD - 1 Jan 2009
Liu Fan, Ikram M Arfan, Janssens A Cecile J W, Schuur Maaike, de Koning Inge, Isaacs Aaron, Struchalin Maksim, Uitterlinden Andre G, den Dunnen Johan T, Sleegers Kristel, Bettens Karolien, Van Broeckhoven Christine, van Swieten John, Hofman Albert, Oostra Ben A, Aulchenko Yurii S, Breteler Monique M B, van Duijn Cornelia M
Abstract excerpt
Several studies have investigated the role of the neuronal sortilin-related receptor (SORL1) gene in Alzheimer's disease (AD), but findings have been inconsistent. We conducted a study of 7 single nucleotide polymorphisms (SNPs), rs668387, rs689021, rs641120, rs1699102, rs3824968, , and , in the SORL1 gene that were associated to AD in previous studies. We tested for association with AD and...
