Article
Meta-analysis of the association between variants in SORL1 and Alzheimer disease.
Archives of neurology - 1 Jan 2011
Reitz Christiane, Cheng Rong, Rogaeva Ekaterina, Lee Joseph H, Tokuhiro Shinya, Zou Fanggeng, Bettens Karolien, Sleegers Kristel, Tan Eng King, Kimura Ryo, Shibata Nobuto, Arai Heii, Kamboh M Ilyas, Prince Jonathan A, Maier Wolfgang, Riemenschneider Matthias, Owen Michael, Harold Denise, Hollingworth Paul, Cellini Elena, Sorbi Sandro, Nacmias Benedetta, Takeda Masatoshi, Pericak-Vance Margaret A, Haines Jonathan L, Younkin Steven, Williams Julie, van Broeckhoven Christine, Farrer Lindsay A, St George-Hyslop Peter H, Mayeux Richard
Abstract excerpt
OBJECTIVE: To reexamine the association between the neuronal sortilin-related receptor gene (SORL1) and Alzheimer disease (AD). DESIGN: Comprehensive and unbiased meta-analysis of all published and unpublished data from case-control studies for the SORL1 single-nucleotide polymorphisms (SNPs) that had been repeatedly assessed across studies. SETTING: Academic research institutions in the United States, the...
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