Article
SORL1 is genetically associated with Alzheimer disease in a Japanese population.
Neuroscience letters - 18 Sept 2009
Kimura Ryo, Yamamoto Mitsuko, Morihara Takashi, Akatsu Hiroyasu, Kudo Takashi, Kamino Kouzin, Takeda Masatoshi
Abstract excerpt
A recent study reported that variants of the neuronal sortilin-related receptor gene (SORL1) increased the risk of late-onset Alzheimer disease (AD) in several populations. Here, we examined the risk effect in a large, well-characterized group of 437 late-onset AD patients and 451 control subjects in a Japanese population. Among eight single-nucleotide polymorphisms (SNPs) of the SORL1 gene for which association...
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