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Article

SORL1 gene, plasma biomarkers, and the risk of Alzheimer's disease for the Han Chinese population in Taiwan.

Alzheimer's research & therapy - 30 Dec 2016

Chou Cheng-Ta, Liao Yi-Chu, Lee Wei-Ju, Wang Shuu-Jiun, Fuh Jong-Ling

Abstract excerpt

BACKGROUND: The sortilin-related receptor 1 (SORL1) gene, regulating the trafficking and recycling of amyloid precursor protein, has been related to Alzheimer's disease (AD) and mild cognitive impairment (MCI). The aim of the present study was to investigate the relationship between SORL1 polymorphisms, plasma concentrations of amyloid-beta (Aβ) isoforms, and AD and MCI susceptibility for a Han Chinese population...

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Source

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Identifiers

PMID: 28034305
DOI: 10.1186/s13195-016-0222-x
PMCID: PMC5200969

Genes

SORL1
APOE

Provenance

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