Article
Implication of sex and SORL1 variants in italian patients with Alzheimer disease.
Archives of neurology - 1 Oct 2009
Cellini Elena, Tedde Andrea, Bagnoli Silvia, Pradella Silvia, Piacentini Silvia, Sorbi Sandro, Nacmias Benedetta
Abstract excerpt
OBJECTIVE: To investigate the association of genetic variants in sortilin-related receptor (SORL1), which has been proposed as an important genetic contributor to late-onset Alzheimer disease (LOAD). DESIGN: We analyzed 13 SORL1 single-nucleotide polymorphisms (SNPs) and the relative haplotypes in a case-control association study. PARTICIPANTS: The sample included 708 Italian subjects: 251 unrelated, sporadic...
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