SORL1 genetic variants modulate risk of amnestic mild cognitive impairment in northern Han Chinese.

doi:10.3109/00207454.2013.850429

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Article

SORL1 genetic variants modulate risk of amnestic mild cognitive impairment in northern Han Chinese.

The International journal of neuroscience - 1 Apr 2014

Gao Xin, Liu Ming, Sun Liang, Qin Bin, Yu Huiyan, Yang Ze, Qi Ruomei, Gao Fangkun

Abstract excerpt

The neuronal sortilin-related receptor (SORL1) has been reported to modulate the risk of Alzheimer's disease (AD) in a variety of populations, but replication studies have been inconsistent. Amnestic mild cognitive impairment (aMCI) is characterized by episodic memory impairment and represents the prodromal stage of AD. However, the relationship between SORL1 and aMCI remains unclear. This study aimed to...

Topics

Aged
Aged, 80 and over
Amnesia
Asian People
Case-Control Studies
Cognitive Dysfunction
Ethnicity
Female
Gene Frequency
Genetic Predisposition to Disease
Haplotypes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

LDL-Receptor Related Proteins

Male

Membrane Transport Proteins

Middle Aged

Polymorphism, Single Nucleotide

Source

Open in PubMed

Identifiers

PMID: 24083537
DOI: 10.3109/00207454.2013.850429

Genes

SORL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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