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Article

Genetic association between SORL1 polymorphisms and Alzheimer's disease in a Japanese population.

Dementia and geriatric cognitive disorders - 1 Jan 2008

Shibata Nobuto, Ohnuma Tohru, Baba Hajime, Higashi Shinji, Nishioka Kenya, Arai Heii

Abstract excerpt

BACKGROUND/AIMS: It has recently been shown that the neuronal sortilin-related receptor (SORL1) plays an important role in the pathogenesis of Alzheimer's disease (AD). METHODS: To investigate whether variations around the SORL1 gene are associated with AD, 7 single-nucleotide polymorphisms (SNPs) were genotyped using TaqMan technology with 180 AD patients and 130 age-matched controls. RESULTS: Our results...

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Source

Identifiers

PMID: 18685254
DOI: 10.1159/000149821

Genes

SORL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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