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Article

A locus on mouse chromosome 13 inversely regulates CD1d expression and the development of invariant natural killer T-cells.

Genes and immunity - 1 Jan 2000

Tsaih S-W, Presa M, Khaja S, Ciecko A E, Serreze D V, Chen Y-G

Abstract excerpt

Invariant natural killer T (iNKT)-cell development is controlled by many polymorphic genes present in commonly used mouse inbred strains. Development of type 1 diabetes (T1D) in NOD mice partly results from their production of fewer iNKT-cells compared with non-autoimmune-prone control strains, including ICR. We previously identified several iNKT-cell quantitative trait genetic loci co-localized with known mouse...

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Source

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Identifiers

PMID: 25654212
DOI: 10.1038/gene.2014.81
PMCID: PMC4409484

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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