Localization of Idd11 is not associated with thymus and nkt cell abnormalities in NOD mice.

doi:10.2337/diabetes.54.12.3453

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Article

Localization of Idd11 is not associated with thymus and nkt cell abnormalities in NOD mice.

Diabetes - 1 Dec 2005

Brodnicki Thomas C, Fletcher Anne L, Pellicci Daniel G, Berzins Stuart P, McClive Peter, Quirk Fiona, Webster Kylie E, Scott Hamish S, Boyd Richard L, Godfrey Dale I, Morahan Grant

Abstract excerpt

Congenic mouse strains provide a unique resource for genetic dissection and biological characterization of chromosomal regions associated with diabetes progression in the nonobese diabetic (NOD) mouse. Idd11, a mouse diabetes susceptibility locus, was previously localized to a region on chromosome 4. Comparison of a panel of subcongenic NOD mouse strains with different intervals derived from the nondiabetic...

Topics

Animals
Chromosome Mapping
Diabetes Mellitus, Type 1
Genetic Predisposition to Disease
Mice
Mice, Inbred C57BL
Mice, Inbred NOD
Thymus Gland

Source

Open in PubMed

Identifiers

PMID: 16306361
DOI: 10.2337/diabetes.54.12.3453

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