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Evidence of genetic epistasis in autoimmune diabetes susceptibility revealed by mouse congenic sublines.

Immunogenetics - 1 Aug 2021

Collin Roxanne, Dugas Véronique, Pelletier Adam-Nicolas, Chabot-Roy Geneviève, Lesage Sylvie

Abstract excerpt

Susceptibility to autoimmune diabetes is a complex genetic trait. Linkage analyses exploiting the NOD mouse, which spontaneously develops autoimmune diabetes, have proved to be a useful tool for the characterization of some of these traits. In a linkage analysis using 3A9 TCR transgenic mice on both B10.BR and NOD.H2k backgrounds, we previously determined that both the Idd2 and Idd13 loci were linked to the...

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PMID: 33755757
DOI: 10.1007/s00251-021-01214-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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Evidence of genetic epistasis in autoimmune diabetes susceptibility revealed by mouse congenic sublines.PMID 33755757Read ↗

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