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Identification of sequence polymorphisms in the D-Loop region of mitochondrial DNA as a risk factor for gastric cancer.

Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis - 1 Jan 2016

Wang Huiying, Wang Yingnan, Zhao Qun, Guo Zhanjun, Zhang Fengbin, Zhao Yue, Zhang Ruixing

Abstract excerpt

The accumulation of single nucleotide polymorphisms (SNPs) in the displacement loop (D-Loop) of mitochondrial DNA (mtDNA) has been identified for their association with cancer risk in different types of cancers. We investigated the gastric cancer risk profile of D-Loop SNPs in a case-control study. The frequent alleles of nucleotides 73G/A, 235A/G, 309C/C insert, 324C/G, 16,362T/C and 16,519C/T were significantly...

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Identifiers

PMID: 25492534
DOI: 10.3109/19401736.2014.926546

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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