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Identification of sequence polymorphisms in the D-loop region of mitochondrial DNA as a risk factor for lung cancer.

Mitochondrial DNA - 1 Aug 2012

Ding Cuimin, Li Ruijuan, Wang Ping, Jin Pule, Li Shengmian, Guo Zhanjun

Abstract excerpt

Accumulation of single nucleotide polymorphisms (SNPs) in the displacement loop (D-loop) of mitochondrial DNA (mtDNA) may be associated with an increased cancer risk. We investigated the lung cancer risk profile of D-loop SNPs in a case-controlled study. The minor alleles of nucleotides 235A/G and 324A/G were associated with an increased risk for lung cancer patients. The minor alleles of the nucleotides 151C/T,...

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Identifiers

PMID: 22708867
DOI: 10.3109/19401736.2012.674120

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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