Article
Identification of sequence nucleotide polymorphisms in the D-loop region of mitochondrial DNA as a risk factor for epithelial ovarian cancer.
Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis - 1 Jan 2016
Liu Shoujuan, Shi Shuhong, Li Yanfang, Kong Desheng
Abstract excerpt
OBJECTIVE: Single nucleotide polymorphisms (SNPs) and mutations in the D-Loop region of mitochondrial DNA have been long proposed to drive the pathogenesis and progression of human malignancies. We investigated the links between SNPs of D-Loop and epithelial ovarian cancer risk. METHOD: Mitochondrial DNA (mtDNA) of peripheral blood from 93 epithelial ovarian cancer patients and controls were examined for single...
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