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Article

Mitochondrial DNA haplogroup N is associated good outcome of gastric cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Dec 2014

Wang Cuiju, Wang Yingnan, Wang Huiying, Zhang Ruixing, Guo Zhanjun

Abstract excerpt

Accumulation of mutations and single nucleotide polymorphisms (SNPs) in the displacement loop (D-loop) of mitochondrial DNA (mtDNA) has been identified for their association with cancer risk and disease outcome in a variety of cancers. We have identified cancer risk-associated D-loop SNPs in gastric cancer patients. In this study, we evaluated the predictive value of these SNPs for cancer outcome. Two SNP sites...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25201064
DOI: 10.1007/s13277-014-2575-8

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