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Identification of sequence polymorphisms in the D-Loop region of mitochondrial DNA as a risk factor for colon cancer.

Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis - 1 Nov 2016

Guo Zhanjun, Zhao Shengnan, Fan Haiyan, Du Yanming, Zhao Yufei, Wang Guiying

Abstract excerpt

The accumulation of single nucleotide polymorphisms (SNPs) in the displacement loop (D-Loop) of mitochondrial DNA (mtDNA) has been identified for their association with cancer risk in a number of cancers. We investigated the colon cancer risk profile of D-Loop SNPs in a case-control study. The frequent alleles of nucleotides 73G/A, 146T/C, 195T/C, 324C/G, 16261C/T, and 16304T/C as well as the minor allele of...

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PMID: 27207371
DOI: 10.3109/19401736.2014.1003920

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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