Article
Mutation in D-loop region of mitochondrial DNA in gastric cancer and its significance.
World journal of gastroenterology - 7 Jun 2005
Zhao Yi-Bing, Yang Hong-Yu, Zhang Xi-Wei, Chen Guo-Yu
Abstract excerpt
AIM: To investigate the mutation in D-loop region of mitochondrial DNA in gastric cancer and its influence on the changes of reactive oxygen species (ROS) and cell cycle. METHODS: The D-loop region was amplified by PCR and sequenced. Reactive oxygen species and cell cycle were detected by flow cytometry in 20 specimens from gastric cancer and adjacent normal tissues. According to the sequence results, gastric...
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