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Mitochondrial DNA mutations and mitochondrial DNA depletion in gastric cancer.

Genes, chromosomes & cancer - 1 Sept 2005

Wu Chew-Wun, Yin Pen-Hui, Hung Wen-Yi, Li Anna Fen-Yau, Li Shu-Hui, Chi Chin-Wen, Wei Yau-Huei, Lee Hsin-Chen

Abstract excerpt

Gastric carcinoma is one of the most common types of cancer in Taiwan. Somatic mitochondrial DNA (mtDNA) alteration in gastric carcinoma and its association with clinicopathologic features remain unclear. When we used polymerase chain reaction (PCR) and direct sequencing, 15 of the 31 (48%) gastric carcinomas displayed somatic mutations in the D-loop region, a hot spot for mutations in mtDNA of human cancers. Ten...

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Identifiers

PMID: 15892105
DOI: 10.1002/gcc.20213

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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