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Association of mtDNA D-loop polymorphisms with risk of gastric cancer in Chinese population.

Pathology oncology research : POR - 1 Sept 2011

Wei Li, Zhao Yong, Guo Tian-kang, Li Pei-qiang, Wu Hua, Xie Han-bing, Ma Ke-jun, Gao Feng, Xie Xiao-dong

Abstract excerpt

The aim of present study was to evaluate the association of common polymorphisms detected in mitochondrial DNA (mtDNA) D-loop region (mononucleotide repetitive D310, single nucleotide polymorphism (SNP) D16521) with susceptibility to gastric cancer (GC) in northwestern Chinese population. A total of 180 GC patients and 218 healthy controls were investigated by using PCR- denaturing high performance liquid...

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PMID: 21461645
DOI: 10.1007/s12253-011-9378-7

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