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Article

LOTUS suppresses axon growth inhibition by blocking interaction between Nogo receptor-1 and all four types of its ligand.

Molecular and cellular neurosciences - 1 Jul 2014

Kurihara Yuji, Iketani Masumi, Ito Hiromu, Nishiyama Kuniyuki, Sakakibara Yusuke, Goshima Yoshio, Takei Kohtaro

Abstract excerpt

Axon growth inhibitors such as Nogo proteins, myelin-associated glycoprotein (MAG), oligodendrocyte myelin glycoprotein (OMgp), and B lymphocyte stimulator (BLyS) commonly bind to Nogo receptor-1 (NgR1), leading to enormous restriction of functional recovery after damage to the adult central nervous system. Recently, we found that lateral olfactory tract usher substance (LOTUS) antagonizes NgR1-mediated Nogo...

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Identifiers

PMID: 25034269
DOI: 10.1016/j.mcn.2014.07.001

Genes

MAG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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LOTUS suppresses axon growth inhibition by blocking interaction between Nogo receptor-1 and all four types of its ligand.PMID 25034269Read ↗

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