Article
A TNF receptor family member, TROY, is a coreceptor with Nogo receptor in mediating the inhibitory activity of myelin inhibitors.
Neuron - 3 Feb 2005
Park Jong Bae, Yiu Glenn, Kaneko Shinjiro, Wang Jing, Chang Jufang, He Xiaolin L, Garcia K Christopher, He Zhigang
Abstract excerpt
A major obstacle for successful axon regeneration in the adult central nervous system (CNS) arises from inhibitory molecules in CNS myelin, which signal through a common receptor complex on neurons consisting of the ligand-binding Nogo-66 receptor (NgR) and two transmembrane coreceptors, p75 and LINGO-1. However, p75 expression is only detectable in subpopulations of mature neurons, raising the question of how...
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