Article
Axonal branching in lateral olfactory tract is promoted by Nogo signaling.
Scientific reports - 21 Dec 2016
Iketani Masumi, Yokoyama Takaakira, Kurihara Yuji, Strittmatter Stephen M, Goshima Yoshio, Kawahara Nobutaka, Takei Kohtaro
Abstract excerpt
Mitral cells are major projection neurons of the olfactory bulb (OB) that form an axonal bundle known as the lateral olfactory tract (LOT). After axonal bundle formation, collateral branches sprout from primary axons of the LOT. Recently, we identified LOT usher substance (LOTUS) as an endogenous Nogo receptor-1 (NgR1) antagonist and demonstrated that LOTUS contributes to the formation of the LOT axonal bundle....
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