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Article

LINGO-1 protein interacts with the p75 neurotrophin receptor in intracellular membrane compartments.

The Journal of biological chemistry - 10 Apr 2015

Meabon James S, De Laat Rian, Ieguchi Katsuaki, Wiley Jesse C, Hudson Mark P, Bothwell Mark

Abstract excerpt

Axon outgrowth inhibition in response to trauma is thought to be mediated via the binding of myelin-associated inhibitory factors (e.g. Nogo-66, myelin-associated glycoprotein, oligodendrocyte myelin glycoprotein, and myelin basic protein) to a putative tripartite LINGO-1·p75(NTR)·Nogo-66 receptor (NgR) complex at the cell surface. We found that endogenous LINGO-1 expression in neurons in the cortex and...

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Identifiers

PMID: 25666623
DOI: 10.1074/jbc.M114.608018
PMCID: PMC4392256

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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