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Article

Reassessment of corticospinal tract regeneration in Nogo-deficient mice.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 8 Jul 2009

Lee Jae K, Chan Andrea F, Luu Sen M, Zhu Yuhong, Ho Carole, Tessier-Lavigne Marc, Zheng Binhai

Abstract excerpt

The myelin-derived neurite growth inhibitor Nogo has been proposed to play a major role in blocking axon regeneration in the CNS after injuries. However, past studies have produced mixed results regarding the regenerative phenotype of various Nogo-deficient mouse lines after experimental spinal cord injury. Two lines did not display enhanced corticospinal tract (CST) regeneration, and one displayed modest...

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Source

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Identifiers

PMID: 19587271
DOI: 10.1523/JNEUROSCI.1864-09.2009
PMCID: PMC2747754

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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