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Article

No Nogo: now where to go?

Neuron - 24 Apr 2003

Woolf Clifford J

Abstract excerpt

Nogo-A, a reticulon protein expressed by oligodendrocytes, contributes to the axonal growth inhibitory action of central myelin in growth cone collapse and neurite outgrowth in vitro assays, and antibody and inhibitor studies have implicated a role for Nogo in regeneration in the adult CNS in vivo. Three independent labs have now produced Nogo knockout mice with, quite unexpectedly, three different regeneration...

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Source

Identifiers

PMID: 12718850
DOI: 10.1016/s0896-6273(03)00233-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

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No Nogo: now where to go?PMID 12718850Read ↗

Reassessment of corticospinal tract regeneration in Nogo-deficient mice.Semantic proximity Read ↗

MAG and OMgp synergize with Nogo-A to restrict axonal growth and neurological recovery after spinal cord trauma.Semantic proximity Read ↗

Systemic deletion of the myelin-associated outgrowth inhibitor Nogo-A improves regenerative and plastic responses after spinal cord injury.Semantic proximity Read ↗

Axon regeneration in young adult mice lacking Nogo-A/B.Semantic proximity Read ↗

Why do Nogo/Nogo‐66 receptor gene knockouts result in inferior regeneration compared to treatment with neutralizing agents?Semantic proximity Read ↗

Constitutive genetic deletion of the growth regulator Nogo-A induces schizophrenia-related endophenotypes.Semantic proximity Read ↗

MiR-182-5p regulates Nogo-A expression and promotes neurite outgrowth of hippocampal neurons <i>in vitro</i>Semantic proximity Read ↗

Nogo-A is critical for pro-inflammatory gene regulation in myocytes and macrophagesSemantic proximity Read ↗

Nogo Provides a Molecular Marker for Diagnosis of Amyotrophic Lateral SclerosisSemantic proximity Read ↗

NgR1 and NgR3 are receptors for chondroitin sulfate proteoglycans.Semantic proximity Read ↗

Prox1 Inhibits Proliferation and Is Required for Differentiation of the Oligodendrocyte Cell Lineage in the MouseSemantic proximity Read ↗

Neutralization of LINGO-1 during In Vitro Differentiation of Neural Stem Cells Results in Proliferation of Immature NeuronsSemantic proximity Read ↗

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