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Article

Coordination of engineered factors with TET1/2 promotes early-stage epigenetic modification during somatic cell reprogramming.

Stem cell reports - 11 Mar 2014

Zhu Gengzhen, Li Yujing, Zhu Fei, Wang Tao, Jin Wensong, Mu Wei, Lin Wei, Tan Weiqi, Li Wenqi, Street R Craig, Peng Siying, Zhang Jian, Feng Yue, Warren Stephen T, Sun Qinmiao, Jin Peng, Chen Dahua

Abstract excerpt

Somatic cell reprogramming toward induced pluripotent stem cells (iPSCs) holds great promise in future regenerative medicine. However, the reprogramming process mediated by the traditional defined factors (OSMK) is slow and extremely inefficient. Here, we develop a combination of modified reprogr...

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Identifiers

PMID: 24672749
DOI: 10.1016/j.stemcr.2014.01.012
PMCID: PMC3964280

Genes

TET1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24672749-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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