Article
NAC1 Regulates Somatic Cell Reprogramming by Controlling Zeb1 and E-cadherin Expression.
Stem cell reports - 12 Sept 2017
Faiola Francesco, Yin Nuoya, Fidalgo Miguel, Huang Xin, Saunders Arven, Ding Junjun, Guallar Diana, Dang Baoyen, Wang Jianlong
Abstract excerpt
Reprogramming somatic cells to induced pluripotent stem cells (iPSCs) is a long and inefficient process. A thorough understanding of the molecular mechanisms underlying reprogramming is paramount for efficient generation and safe application of iPSCs in medicine. While intensive efforts have been devoted to identifying reprogramming facilitators and barriers, a full repertoire of such factors, as well as their...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
