Article

Induced Pluripotency: Current Reprogramming Methods and Areas for Improved Therapeutic Capabilities

2023-10-22

Abstract excerpt

The discovery of the Yamanaka factors allowed scientists to induce pluripotency in a way that was unachievable before, but the implementation proved to be complex. Previous methods in cellular reprogramming often create problems with temporal control of the reprogramming genes, site-specific delivery, and insertional mutagenesis. One of the methods used to control gene expression with adenovirus is the Tet-On syst...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9f07cad7-1a55-55a5-b303-78921968cfa3
DOI: 10.14293/pr2199.000455.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Induced Pluripotency: Current Reprogramming Methods and Areas for Improved Therapeutic CapabilitiesDOI 10.14293/pr2199.000455.v1Read

Induced Pluripotency: A Powerful Tool for In Vitro ModelingSemantic proximity Read

Induced pluripotent stem cells: opportunities and challengesSemantic proximity Read

Ten years of progress and promise of induced pluripotent stem cells: historical origins, characteristics, mechanisms, limitations, and potential applicationsSemantic proximity Read

Direct Reprogramming into Desired Cell Types by Defined FactorsSemantic proximity Read

Concise Review: Oct4 and More: The Reprogramming ExpresswaySemantic proximity Read

Direct cell-fate conversion of somatic cells: Toward regenerative medicine and industriesSemantic proximity Read

Mechanistic insights into reprogramming to induced pluripotencySemantic proximity Read

Direct cell reprogramming for tissue engineering and regenerative medicineSemantic proximity Read

Concise Review: The Magic Act of Generating Induced Pluripotent Stem Cells: Many Rabbits in the HatSemantic proximity Read

Reprogramming somatic cells towards pluripotency by defined factorsSemantic proximity Read

Induced Pluripotent Stem Cells: Fundamentals and Applications of the Reprogramming Process and its Ramifications on Regenerative MedicineSemantic proximity Read

Engineering Cell Fate: The Roles of iPSC Transcription Factors, Chemicals, Barriers and Enhancing Factors in Reprogramming and TransdifferentiationSemantic proximity Read