Article
A modular open platform for systematic functional studies under physiological conditions.
Nucleic acids research - 30 Sept 2015
Mulholland Christopher B, Smets Martha, Schmidtmann Elisabeth, Leidescher Susanne, Markaki Yolanda, Hofweber Mario, Qin Weihua, Manzo Massimiliano, Kremmer Elisabeth, Thanisch Katharina, Bauer Christina, Rombaut Pascaline, Herzog Franz, Leonhardt Heinrich, Bultmann Sebastian
Abstract excerpt
Any profound comprehension of gene function requires detailed information about the subcellular localization, molecular interactions and spatio-temporal dynamics of gene products. We developed a multifunctional integrase (MIN) tag for rapid and versatile genome engineering that serves not only as a genetic entry site for the Bxb1 integrase but also as a novel epitope tag for standardized detection and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
