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Article

Correlation of genetic risk and messenger RNA expression in a Th17/IL23 pathway analysis in inflammatory bowel disease.

Inflammatory bowel diseases - 1 May 2014

Fransen Karin, van Sommeren Suzanne, Westra Harm-Jan, Veenstra Monique, Lamberts Letitia E, Modderman Rutger, Dijkstra Gerard, Fu Jingyuan, Wijmenga Cisca, Franke Lude, Weersma Rinse K, van Diemen Cleo C

Abstract excerpt

BACKGROUND: The Th17/IL23 pathway has both genetically and biologically been implicated in the pathogenesis of the inflammatory bowel diseases (IBD), Crohn's disease, and ulcerative colitis. So far, it is unknown whether and how associated risk variants affect expression of the genes encoding for Th17/IL23 pathway proteins. METHODS: Ten IBD-associated SNPs residing near Th17/IL23 genes were used to construct a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24662057
DOI: 10.1097/MIB.0000000000000013

Genes

CCR6
RORC
STAT3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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